TY - JOUR
T1 - A Deep Learning Framework for the Prediction and Diagnosis of Ovarian Cancer in Pre- and Post-Menopausal Women
AU - Ziyambe, Blessed
AU - Yahya, Abid
AU - Mushiri, Tawanda
AU - Tariq, Muhammad Usman
AU - Abbas, Qaisar
AU - Babar, Muhammad
AU - Albathan, Mubarak
AU - Asim, Muhammad
AU - Hussain, Ayyaz
AU - Jabbar, Sohail
N1 - Publisher Copyright:
© 2023 by the authors.
PY - 2023/5
Y1 - 2023/5
N2 - Ovarian cancer ranks as the fifth leading cause of cancer-related mortality in women. Late-stage diagnosis (stages III and IV) is a major challenge due to the often vague and inconsistent initial symptoms. Current diagnostic methods, such as biomarkers, biopsy, and imaging tests, face limitations, including subjectivity, inter-observer variability, and extended testing times. This study proposes a novel convolutional neural network (CNN) algorithm for predicting and diagnosing ovarian cancer, addressing these limitations. In this paper, CNN was trained on a histopathological image dataset, divided into training and validation subsets and augmented before training. The model achieved a remarkable accuracy of 94%, with 95.12% of cancerous cases correctly identified and 93.02% of healthy cells accurately classified. The significance of this study lies in overcoming the challenges associated with the human expert examination, such as higher misclassification rates, inter-observer variability, and extended analysis times. This study presents a more accurate, efficient, and reliable approach to predicting and diagnosing ovarian cancer. Future research should explore recent advances in this field to enhance the effectiveness of the proposed method further.
AB - Ovarian cancer ranks as the fifth leading cause of cancer-related mortality in women. Late-stage diagnosis (stages III and IV) is a major challenge due to the often vague and inconsistent initial symptoms. Current diagnostic methods, such as biomarkers, biopsy, and imaging tests, face limitations, including subjectivity, inter-observer variability, and extended testing times. This study proposes a novel convolutional neural network (CNN) algorithm for predicting and diagnosing ovarian cancer, addressing these limitations. In this paper, CNN was trained on a histopathological image dataset, divided into training and validation subsets and augmented before training. The model achieved a remarkable accuracy of 94%, with 95.12% of cancerous cases correctly identified and 93.02% of healthy cells accurately classified. The significance of this study lies in overcoming the challenges associated with the human expert examination, such as higher misclassification rates, inter-observer variability, and extended analysis times. This study presents a more accurate, efficient, and reliable approach to predicting and diagnosing ovarian cancer. Future research should explore recent advances in this field to enhance the effectiveness of the proposed method further.
KW - augmentation
KW - convolutional neural networks
KW - diagnosis
KW - epithelial ovarian cancer
KW - histopathological images
KW - prediction
UR - https://www.scopus.com/pages/publications/85160576810
UR - https://www.scopus.com/pages/publications/85160576810#tab=citedBy
U2 - 10.3390/diagnostics13101703
DO - 10.3390/diagnostics13101703
M3 - Article
AN - SCOPUS:85160576810
SN - 2075-4418
VL - 13
JO - Diagnostics
JF - Diagnostics
IS - 10
M1 - 1703
ER -