Complete genome sequence of an antimicrobial-producing Bacillus velezensis Sam8H1 isolate from the Makgadikgadi saltpans of Botswana

Gorata Modikwe; Lokeshwaran Manoharan; Gomolemo Mabutho; Kebaneilwe Lebani; Lesedi Lebogang; Nerve Zhou

doi:10.1128/MRA.00175-21

Complete genome sequence of an antimicrobial-producing Bacillus velezensis Sam8H1 isolate from the Makgadikgadi saltpans of Botswana

Gorata Modikwe
, Lokeshwaran Manoharan
, Gomolemo Mabutho
, Kebaneilwe Lebani
, Lesedi Lebogang
, Nerve Zhou

Research output: Contribution to journal › Article › peer-review

Abstract

The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene clusters important for genome-guided drug discovery studies.

Original language	English
Article number	e00175-21
Number of pages	3
Journal	Microbiology Resource Announcements
Volume	10
Issue number	17
DOIs	https://doi.org/10.1128/MRA.00175-21
Publication status	Published - Apr 2021

All Science Journal Classification (ASJC) codes

Molecular Biology
Immunology and Microbiology (miscellaneous)
Genetics

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abstract = "The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene clusters important for genome-guided drug discovery studies.",

author = "Gorata Modikwe and Lokeshwaran Manoharan and Gomolemo Mabutho and Kebaneilwe Lebani and Lesedi Lebogang and Nerve Zhou",

note = "Funding Information: This work was funded by the Department of Research and Innovation Initiation grant number R00026 at the Botswana International University of Science and Technology, Botswana. We declare no conflicts of interest. Publisher Copyright: Copyright {\textcopyright} 2021 Modikwe et al.",

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language = "English",

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AU - Modikwe, Gorata

AU - Manoharan, Lokeshwaran

AU - Mabutho, Gomolemo

AU - Lebani, Kebaneilwe

AU - Lebogang, Lesedi

AU - Zhou, Nerve

N1 - Funding Information: This work was funded by the Department of Research and Innovation Initiation grant number R00026 at the Botswana International University of Science and Technology, Botswana. We declare no conflicts of interest. Publisher Copyright: Copyright © 2021 Modikwe et al.

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Y1 - 2021/4

N2 - The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene clusters important for genome-guided drug discovery studies.

AB - The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene clusters important for genome-guided drug discovery studies.

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Complete genome sequence of an antimicrobial-producing Bacillus velezensis Sam8H1 isolate from the Makgadikgadi saltpans of Botswana

Abstract

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