Irreversibility analysis of an unsteady micropolar CNT-blood nanofluid flow through a squeezing channel with activation energy-Application in drug delivery

N. Naresh Kumar, D. R.V.S.R.K. Sastry, Sachin Shaw

Research output: Contribution to journalArticlepeer-review

Abstract

Background and objective: Due to the low toxicity, unique physiochemical properties, and appropriate surface modifications, Carbon Nanotubes (CNTs) are used as target carriers in drug delivery systems. In the present problem, we have considered both single-walled and multi-walled CNTs to study the impact of irreversibility on the micropolar nanofluid flow through a squeezing channel with the base fluid blood. The blood is considered a micropolar fluid in the presence of different blood cells and their rotational nature. Further, blood is influenced by the external magnetic field parallel to the microrotation along with viscous and Joule dissipations. Method: Highly coupled and nonlinear partial differential equations are solved with Homotopy Analysis Method (HAM) after simplified equations using similarity transformation. Further, we have concluded the minimum squared residual errors to show the method's accuracy. A comparison made with the existing literature and shows a good agreement. Results: The angular velocity of the fluid particles is enhanced by increasing the squeezing number. In the case of the squeezing, volume fraction has improved the viscous drag and is found high for MWCNT embedded nanofluid. The heat transfer rate is higher for the MWCNT embedded nanofluid than the SWCNT embedded nanofluid. A descent found in entropy generation boosts up with the Brinkman parameter while opposite phenomena appear for radiation and Hartman number and vortex viscosity. Both Bejan number and entropy generation profiles are restricted with an increase in vortex viscosity. Conclusion: SWCNTs are showed to be more effective and efficient than the MWCNTs in elevating velocity, temperature and irreversibility of the system. Outcomes of this problem will help to understand the implementation of the drug carrier and irreversibility phenomena during drug delivery.

Original languageEnglish
Article number107156
JournalComputer Methods and Programs in Biomedicine
Volume226
DOIs
Publication statusPublished - Nov 2022

All Science Journal Classification (ASJC) codes

  • Software
  • Computer Science Applications
  • Health Informatics

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