Nanoenvironmental Effects Dramatically Influence the Sensitivity of Immunoassays

B. Mattiasson; K. Teeparuksapun; L. Lebogang; M. Hedström

doi:10.1016/j.tibtech.2017.06.001

Nanoenvironmental Effects Dramatically Influence the Sensitivity of Immunoassays

B. Mattiasson, K. Teeparuksapun, L. Lebogang, M. Hedström

Biological & Biotechnological Sciences

Research output: Contribution to journal › Short survey › peer-review

Abstract

It is possible to improve the sensitivity of immunoassays by several orders of magnitude by exploiting nanoenvironmental effects. This approach can detect trace amounts of compounds and will better illuminate the presence of signal substances in biological systems. Here we describe a method for ultrasensitive immunoassays using ‘normal’ antibodies (Abs).

Original language	English
Pages (from-to)	1021-1024
Number of pages	4
Journal	Trends in Biotechnology
Volume	35
Issue number	11
DOIs	https://doi.org/10.1016/j.tibtech.2017.06.001
Publication status	Published - Nov 2017

All Science Journal Classification (ASJC) codes

Biotechnology
Bioengineering

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10.1016/j.tibtech.2017.06.001

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title = "Nanoenvironmental Effects Dramatically Influence the Sensitivity of Immunoassays",

abstract = "It is possible to improve the sensitivity of immunoassays by several orders of magnitude by exploiting nanoenvironmental effects. This approach can detect trace amounts of compounds and will better illuminate the presence of signal substances in biological systems. Here we describe a method for ultrasensitive immunoassays using {\textquoteleft}normal{\textquoteright} antibodies (Abs).",

author = "B. Mattiasson and K. Teeparuksapun and L. Lebogang and M. Hedstr{\"o}m",

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AU - Mattiasson, B.

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AU - Hedström, M.

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AB - It is possible to improve the sensitivity of immunoassays by several orders of magnitude by exploiting nanoenvironmental effects. This approach can detect trace amounts of compounds and will better illuminate the presence of signal substances in biological systems. Here we describe a method for ultrasensitive immunoassays using ‘normal’ antibodies (Abs).

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Nanoenvironmental Effects Dramatically Influence the Sensitivity of Immunoassays

Abstract

All Science Journal Classification (ASJC) codes

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