Wave instability of intercellular Ca2+ oscillations

C. B. Tabi, I. Maïna, A. Mohamadou, H. P.Ekobena Fouda, T. C. Kofané

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


Modulational instability is exclusively addressed in a minimal model for calcium oscillations in cells. The cells are considered to be coupled through paracrine signaling. The endoplasmic recticulum and cytosolic Ca2+ equations are reduced to a single differential-difference amplitude equation. The linear stability analysis of a plane wave is performed on the latter and the paracrine coupling parameter is shown to deeply influence the instability features. Our analytical expectations are confirmed by numerical simulations, as instability regions give rise to unstable Ca2+ wave patterns. We also discuss the possibility of perfect intercellular communication via the activation of modulational instability.

Original languageEnglish
Article number18005
Issue number1
Publication statusPublished - Jan 1 2014

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)


Dive into the research topics of 'Wave instability of intercellular Ca2+ oscillations'. Together they form a unique fingerprint.

Cite this